The 18 amino acids in bovine collagen and how they can improve your health

Apr 27, 2026

While there are 18 amino acids in bovine collagen, it is the presence of key amino acids that lends the majority of the perks: glycine, proline, and hydroxyproline.

These three amino acids are crucial building blocks of collagen, tendons, and ligaments and have been shown to support health in a number of other ways, such as promoting normal inflammatory processes and supporting immune function.*

Summary

• This piece highlights glycine, proline, and hydroxyproline as the primary amino acids responsible for bovine collagen’s benefits, including support for connective tissues, normal inflammatory processes, and immune function.
• It emphasises L-glycine (described here as essential) as an immune booster with antiviral properties and links to a 2003 review on glycine’s anti-inflammatory, immunomodulatory, and cytoprotective effects.

L-Glycine and Immune Support

L-Glycine is an essential amino acid, meaning that your body needs it, but cannot produce it on its own. It is an immune system booster as it helps build antibodies and has important antiviral properties.

Totally Derma® Collagen contains this important amino acid, and as a result, by taking 10,000mg of collagen daily you are boosting your immune system.

Research Highlight (Abstract)

Curr Opin Clin Nutr Metab Care. 2003 Mar;6(2):229-40.
L-Glycine: a novel anti-inflammatory, immunomodulatory, and cytoprotective agent.
Zhong Z1, Wheeler MD, Li X, Froh M, Schemmer P, Yin M, Bunzendaul H, Bradford B, Lemasters JJ.

PURPOSE OF REVIEW:
In recent years, evidence has mounted in favour of the anti-inflammatory, immunomodulatory and cytoprotective effects of the simplest amino acid L-glycine.

This article will focus on the recent findings about the responsible mechanisms of protection and review the beneficial effects of glycine in different disease states.

Read more here: https://www.ncbi.nlm.nih.gov/pubmed/12589194

Why Totally Derma® Collagen Peptides?

Totally Derma® collagen peptides have an exceptional absorption rate via the small intestine; the peptides that are consumed circulate through the body’s bloodstream instead of going through the digestive tract.

Since Totally Derma® is broken down to a low molecular level, this ensures that the amino acids and nutrients are easily and quickly, absorbed into the bloodstream.

Contact and Product Information

Please contact us if you would like further information, clinical studies, or would like to become one of our Clinic Partners. You can also explore our collagen products for additional options.

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Frequently Asked Questions

Which amino acids in bovine collagen are most important for its health benefits?

The article highlights glycine, proline, and hydroxyproline as the key amino acids. These are core building blocks of collagen, tendons, and ligaments and are described as supporting normal inflammatory processes and immune function.

How is L-glycine portrayed in this piece, and what benefits are cited?

The piece describes L-glycine as “essential,” emphasising its role in immune support by helping build antibodies and noting antiviral properties. It cites a 2003 review reporting glycine’s anti-inflammatory, immunomodulatory, and cytoprotective effects. (General nutrition texts often classify glycine as nonessential or conditionally essential, but the article presents it as essential in this context.)

What daily amount of collagen does the article suggest, and what outcome is claimed?

It suggests taking 10,000 mg (10 g) of Totally Derma® collagen daily, claiming this boosts the immune system due to its glycine content.

What makes Totally Derma® collagen peptides different, according to the article?

They are described as being broken down to a low molecular level for exceptional absorption via the small intestine, allowing the peptides to enter the bloodstream efficiently and deliver amino acids and nutrients quickly.

Where can I find supporting research or get more information?

The piece references a 2003 review on L-glycine’s anti-inflammatory, immunomodulatory, and cytoprotective actions (Curr Opin Clin Nutr Metab Care. 2003 Mar;6(2):229–40; PubMed).