Hormone Rebalancing Solution
Science-backed solution for hormone balance, cellular health, and lasting vitality
How does Totally Derma® help with Hormonal Health?
Totally Derma® helps with hormonal rebalancing primarily by addressing the physiological effects of hormonal shifts—particularly during perimenopause and menopause—on the body's collagen levels, gut health, and inflammation.
The transition into menopause often triggers a rapid decline in collagen—up to 30% can be lost in the first five years alone. This loss isn't just about wrinkles; it affects everything from your joints to your intimate health.
Totally Derma® is a high-strength "nutraceutical" (a medical-grade supplement) designed to address these systemic changes by stimulating the body's natural production of collagen, elastin, and hyaluronic acid.
One of the most significant benefits for menopausal women is its impact on "gynaecological dryness."
By significantly increasing Hyaluronic Acid (HA) levels, it helps rehydrate mucous membranes throughout the body which greatly alleviates vaginal dryness.
“Boost your immune system with Totally Derma®. Especially important for menopausal women.Low oestrogen means a low immune response, amazing product”.
Dr Suren Naidoo
Women’s Clinic, Mens Health Clinic, London, UK
Totally Derma® conducted a small clinical menopausal health trial for its own formulation in 2021 to assess the effects of the symptoms associated with perimenopause and menopause; women reported a 70% improvement in more severe menopausal symptoms, including improvements in vaginal dryness and urge and stress urinary issues, reduced pain during sex and less external irritation.
The study primarily focused on Genitourinary Syndrome of Menopause (GSM)—which includes vaginal dryness and urinary issues—as well as the more visible effects of estrogen loss on skin, hair, and nails.
Key Study Findings
The results (often cited in the 2021/2022 data) showed significant improvements across several categories over a 12-week period:
Genitourinary Symptoms (GSM)
%
Overall improvement in GSM symptoms
%
Of participants reported that bleeding after intercourse had stopped.
%
Reported improvement in stress urinary incontinence.
%
Reported improvement in vaginal dryness.
Skin & Appearance
%
Improvement in nail strength and appearance.
%
Improvement in skin texture.
%
Improvement in skin hydration.
%
Improvement in hair growth and thickness.
General Wellbeing
%
Reduction in skin itchiness (a common but underreported menopause symptom).
%
Improvement in joint pain and flexibility.
Skin "Bounce" and Hydration
As oestrogen levels drop, skin becomes thinner and drier (often called "menopause skin").
Totally Derma® includes Type I - 10,000mg enzymatically hydrolysed collagen to provide the essential amino acids needed to rebuild the skin's structure, and increase firmness, reducing the "crepey" texture and sagging common in the cheeks and jawline. It also contains 210mg of Hyaluronic acid to help prevent skin dehydration and increase the glow and radiance within the skin.
Because it includes high-dose antioxidants (like Green Tea and Grapeseed extract), it helps combat the oxidative stress that accelerates ageing during this hormonal shift and reduces inflammation.
Healthy Joints
Oestrogen protects joints and bone density. When it disappears, many women experience sudden "aching joints."
Lubrication and hydration are what we are all seeking in joints. The high levels of Hyaluronic Acid act as a lubricant for the joints, making movement more "fluid" and less painful.
Totally Derma® contains Type II collagen, which specifically targets cartilage and connective tissue, helping to keep bones and joints more resilient.
The Skin-Gut-Hormone Connection
Menopause can sometimes wreak havoc on digestion.
Gut Lining: Collagen helps "heal and seal" the gut lining if we have leaky gut, where “bad for us” toxins and food particles escape and leak into our blood stream. A healthy gut is crucial because the estrobolome (a collection of bacteria in the gut) helps metabolise and clear oestrogen. By supporting gut health, with Type III collagen amino acid peptides, Totally Derma® indirectly supports better hormonal balance.
Menopause can sometimes wreak havoc on digestion.
Gut Lining: Collagen helps "heal and seal" the gut lining if we have leaky gut, where “bad for us” toxins and food particles escape and leak into our blood stream. A healthy gut is crucial because the estrobolome (a collection of bacteria in the gut) helps metabolise and clear oestrogen. By supporting gut health, with Type III collagen amino acid peptides, Totally Derma® indirectly supports better hormonal balance.
Ingredients and Why it matters for Menopause
Ingredient
Metabolic Benefit
10,000mg Arthred® Collagen
High dose and high-strength (10,000mg) bovine collagen peptide designed for superior absorption to support skin, hair, nails, bones, and joints needed to counteract rapid menopause collagen loss.
210mg Hyaluronic Acid
Therapeutic dose for internal hydration and retaining moisture in the skin and mucous membranes (address skin, eyes and vaginal dryness)
Antioxidants
Reduce the systemic inflammation often triggered by low oestrogen.
Vitamin C
Essential co-factor that tells your body to actually use the collagen and supports skin elasticity, joint health and bone density.
Zinc
Supports immune health, reducing "inflammaging" (chronic inflammation) and supports thyroid function.
Grape Seed Extract
Acts as a potent antioxidant; studies suggest it may help reduce hot flashes and insomnia.
Green Tea Extract
Supports metabolism, aiding weight management. Rich in antioxidants like EGCG, helps reduce inflammation.
Alpha Lipoic Acid
Assists with metabolic changes, weight gain, oxidative stress, and bone density loss.
Copper & Manganese
Essential minerals that act as co-factors for the body to actually synthesize new collagen.
The amino acid peptides in the Totally Derma® formula help manage the body's stress hormone, cortisol, and support the balance of estrogen, which is critical for skin health, reducing acne, rosacea, and eczema.
By repairing the gut lining with Type III collagen amino acid peptides within the formulation, Totally Derma® optimises gut health, which is essential for regulating hormones that affect skin health.
It reduces high levels of systemic inflammation, often brought on by imbalanced hormones, which can cause skin ageing.
Replenish
re•plen•ish
verb
1. fill (something) up again.
◦ restore a former level or condition
Rejuvenate
re•ju•ve•nate
verb
1. give new energy or vigour to; revitalise.
◦ restore a youthful appearance to
Repair
re•pair
verb
1. fix or mend (something suffering from damage).
Real Client Stories
Hear directly from people who transformed their skin health
I have been using this for about 5 months now and am extremely happy with the results. In addition to seeing an improvement in my skin, hair and nails - the best thing for me is the reduction in some of my menopause symptoms. I was experiencing terrible aching joints, particularly at night. Since taking Totally Derma daily (I add it to my breakfast smoothie) these aches have practically disappeared.
Lesley Wilsdon
Happy Customer
My job involves standing for long hours at a time. I had constant pain in my joints, but after using Totally Derma it has really diminished my pain. I also find great improvements in my hair, skin and my nails. My hair is thicker and my nails are growing longer and stronger and my skin feels smoother and less wrinkled. I am 69 years old and I would not hesitate to recommend this product!
Pierre Vassiliou
Happy Customer
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The Science Behind Wellness
Explore the clinical research and evidence supporting our wellness formulations