Medical aesthetic practitioners may wish to consider including nutraceutical supplementation as an adjunct solution to support (invasive and non-invasive) aesthetic treatments, to ensure the best possible outcome of any procedures they undertake in clinic.
Totally Derma® benefits
Totally Derma® is a unique pharma-grade, nutraceutical supplement which supports anti-ageing of the skin from the inside; by stimulating the body's optimal production of collagen, elastin, and hyaluronic acid, addressing both the physical signs of the ageing process (aging process) and the underlying physiological processes.
The ingredients in Totally Derma® are digested and distributed via the blood vessels into the deeper layers of the skin (dermis), where they multiply and stimulate fibroblast cells to produce more collagen and hyaluronic acid in the dermis, increasing collagen in the skin.
Totally Derma® contains a world-renowned superior form of hydrolysed (bovine) collagen known as Arthred®. It contains 18 amino acids including: glycine, proline, hydroxylysine, lysine and hydroxyproline via a PHARMAGRADE manufacturing process in Germany.
Arthred® is enzymatically processed (meaning it is deemed as ‘pre-digested’ – the amino acids reach the small intestine, undamaged by digestive enzymes and are optimally absorbed there) which allows for a scientifically proven 95% absorption rate due to its tiny molecular size (3 kDa); this far exceeds regular collagen supplements which average a larger size of molecule (70 kDa) and therefore have inferior absorption.
This ensures the Arthred® collagen passes the gut barrier and is then distributed via the blood circulation to the fibroblasts, which are then clinically shown to be stimulated and increase their collagen production by fourfold. These fibroblasts are also shown to increase in size and number after consuming Arthred® for 4 weeks.
Totally Derma®also contains Synovoderma® Hyaluronic Acid which, like Arthred®, holds a 95% scientifically proven absorption level for maximum results. Most Hyaluronic Acid supplements are poorly absorbed and are therefore minimally effective. Synovoderma® is clinically shown to dramatically increase hydration within the skin and improve skin elasticity. These two key ingredients of Arthred® and Synovoderma® ensure the impressive increase of collagen and hydration as shown within TotallyDerma® skin study trials.
Totally Derma® also differs from other collagen supplements by addressing cross-linking issues with 5 key antioxidant ingredients, where each active ingredient is selected for synergistic effect.

Totally Derma® inclusion in treatments (as an add on) as well as included in a treatment course / aesthetic devices
The aesthetic industry provides us with high quality injectables, highly effective active topical products, plus a whole array of high-tech lasers, facials, microdermabrasion devices, peels, microneedling, etc, which all help to stimulate and boost collagen in the skin, thus giving us a more youthful appearance.
As highly efficacious as these aesthetic solutions are, it is important to consider stimulating collagen from the inside, rather than just working externally. After all, collagen-producing fibroblast skin cells are found in the deeper layers of the skin, so it makes sense to also stimulate them from inside the body.
The biggest advantage to adding Totally Derma® with aesthetic treatments, is that collagen and hyaluronic acid are increased all over the body, not just in a targeted area so it really does enhance general well being. The overall skin quality of the body improves, as do general joint achesand aches and pains, in addition, clients comment that their hair and nails are much healthier and stronger. Women in their menopausal years can also experience a relief in vaginal dryness and discomfort.
From a gut-health point of view, the biggest digestive benefit of consuming more collagen is that it helps form connective tissue and therefore “seals and heals” the protective lining of the gastrointestinal tract. This can produce improvements in skin conditions like cystic-acne, rosacea and eczema if the root cause is poor gut health and not hormonal.
Totally Derma® partnered with collagen stimulating injectables
Whilst many patients seek out injectable treatments to balance their facial features and replace lost volume,aesthetic practitioners may wish to address any inflammatory issues that may be occurring simultaneously.
Physiological and aesthetic issues are caused by inflammation in the body which can show up on the skin.

The words “anti-inflammatory” have been over-used, however, the use of anti-inflammatory ingredients in effectively formulated products will help to prevent harmful inflammation and premature aging.
Boley Nutraceuticals Ltd., the developers of Branded Totally Derma® have specifically designed a nutraceutical formulation to help reduce inflammation in both the skin and the body. A formulation that contains specific ingredients in specific dosages which can really help with this problem.

Totally Derma® partnered with skin peels
Hormone-appropriate supplements are usually recommended for skin peel recovery, as are the latest active ingredients. However, oral antioxidants can exert a generalised benefit, being steady and subtle, but undoubtedly profound. Crucially oral antioxidants contribute to rapid and strong wound healing post peel.
To complete its anti-ageing, skin healing properties, Totally Derma® also contains an additional seven critical co-factors which further enhance the benefits of oral collagen and hyaluronic acid. These include 5 powerful antioxidants: GrapeSeed Extract, Green Tea extract, Vitamin C, Alpha Lipoic Acid, Zinc, Manganese and Copper.
The combination of all these ingredients not only help to make more collagen in the skin but they also assist in repairing skin damage and inflammation.
Totally Derma® as part of a homecare regime
Today’s busy lifestyles don’t always allow for adequate fresh organic green vegetables or a wholly raw food diet, so it is important to integrate solutions that provide the richest possible source of absorbable, active nutrients.
When it comes to a homecare skincare regime, two mainstays are corrective (antioxidants to neutralise free-radical damage) and protective (the use of adequate physical or chemical sun protection).

Totally Derma® is a total nutraceutical (oral) solution containing therapeutic dosages of bovine collagen amino acid peptides, hyaluronic acid, antioxidants, vitamins and minerals – all are essential components of a therapeutic skincare regime.
Totally Derma® is an effective, natural product especially great for those who are 35 years plus, as part of their skincare regime. Totally Derma® is really easy to take, just one scoop mixed in water before bed every day is all that’s needed. It is pleasant tasting and easy to incorporate into the bedtime routine. Consuming it at night helps to take advantage of the body’s own optimal collagen production which happens in the first few hours of sleep.
Q&A
Question: What is Totally Derma® and why integrate it into clinic protocols?
Short answer: Totally Derma® is positioned as a pharma-grade nutraceutical designed to complement aesthetic procedures by stimulating collagen, elastin, and hyaluronic acid from within. It aims to enhance outcomes from injectables, peels, devices, and topical homecare by improving skin hydration, elasticity, and overall skin quality systemically—not just at treated sites. It is especially suited to adults 35+ and is intended as a simple, once-daily adjunct to in-clinic treatments and at-home regimens.
Question: What makes Totally Derma® different from typical collagen supplements?
Short answer: Its core actives are Arthred® hydrolysed (bovine) collagen and Synovoderma® hyaluronic acid, both described as having 95% absorption. Arthred® is enzymatically “pre-digested,” with a small 3 kDa molecular size (vs. ~70 kDa in many standard collagens), to support optimal absorption and delivery via the microcirculation to dermal fibroblasts. In studies cited, fibroblasts increased collagen production fourfold and increased in size and number after 4 weeks of Arthred® intake. Synovoderma® hyaluronic acid is reported to markedly increase skin hydration and elasticity. The formula also targets collagen cross-linking and skin repair with co-factors including Grape Seed Extract, Green Tea extract, Vitamin C, Alpha Lipoic Acid, plus the minerals Zinc, Manganese, and Copper.
Question: How do you use Totally Derma®, and who is it best for?
Short answer: Take one scoop mixed in water each evening. Nighttime dosing is recommended to align with the body’s peak collagen production in the first hours of sleep. It is presented as an effective, natural option for adults—particularly those 35+—to integrate into daily homecare alongside corrective antioxidants and sun protection.
Question: How does Totally Derma® pair with injectables, peels, and devices?
Short answer: It’s positioned as an inside-out complement to externally focused procedures. With collagen- and HA-supportive actives and anti-inflammatory, antioxidant co-factors, it aims to reduce inflammation that can accompany aesthetic treatments, support faster, stronger wound healing post-peel, and enhance skin quality systemically. Because it works body-wide, it can support overall skin health beyond the specific, targeted treatment areas addressed by injectables or devices.
Question: What broader benefits are described beyond skin appearance?
Short answer: Reported whole-body benefits include improved skin hydration and elasticity, greater joint comfort, and stronger hair and nails. Women in menopausal years may experience relief from vaginal dryness and discomfort. From a gut-health perspective, increased collagen intake may help “seal and heal” the gastrointestinal lining, which can translate to improvements in cystic acne, rosacea, and eczema when poor gut health—rather than hormonal factors—is the root cause.
