Joint Health /
Physically Active
Science-backed solution for hormone balance, cellular health, and lasting vitality
How can Totally Derma® improve joint health?
Totally Derma® high-strength, powdered nutraceutical drink designed to improve joint mobility and comfort by stimulating the body’s natural production of collagen and hyaluronic acid which declines with age. Originally formulated for medical joint care in osteoarthritis patients, it uses a highly absorbable (95% absorption rate) bovine collagen peptide called Arthred®, which helps to regenerate cartilage at a cellular level. It functions as a "repair and lubricate" system from the inside out.
Mechanism of Action
- High-Absorption Collagen (Arthred®): Totally Derma uses 10,000mg of Arthred®, a patented, pre-digested (hydrolysed) bovine collagen that is very small in molecular size (2-3 kDa), allowing it to be absorbed efficiently into the bloodstream.
- Cartilage Support: Once in the blood, the amino acid peptides are transported to joints, acting as raw materials for cartilage cells. Studies on the ingredients, particularly the Arthred® hydrolysed collagen, have demonstrated an increase in cartilage thickness and a reduction in joint pain. Read more about Arthred®.
- Synergistic Ingredients: In addition to collagen, it contains a therapeutic dose of Synovoderma (hyaluronic acid) and co-factors like Vitamin C, Zinc, and Copper, which aid in repairing connective tissue.
Rebuilds Cartilage with Arthred® - Rebuilding the Cushion
The "hero" ingredient is Arthred®, a patented bovine hydrolysed collagen. Unlike standard collagen, these are short-chain amino acid peptides that are 95% absorbed into the bloodstream.
- The Science: These peptides specifically resemble the amino acid composition of human joint cartilage.
- The Result: It helps repair and rebuild the cartilage matrix, which is essential for those with osteoarthritis or general age-related wear and tear. Unlike standard collagen supplements that may only offer 2,000mg to 5,000mg, Totally Derma® provides a therapeutic dose of 10,000mg of Arthred® collagen peptides.
- Targeted Amino Acids: It is rich in proline, glycine, and hydroxyproline—the specific building blocks your body needs to "knit" together damaged connective tissue.
Lubricates "Stiff" Joints
Totally Derma® contains a therapeutic dose (210mg) of Synovoderma® Hyaluronic Acid (HA).
- The Function: HA is the primary component of synovial fluid, which acts as a shock absorber and lubricant for your joints.
- The Result: Increasing internal HA levels helps "grease the wheels," reducing that "crunchy" or stiff feeling in the knees, hips, and spine.
Reduces Inflammation
The formula includes a "cocktail" of antioxidants and minerals that address the physiological stress on joints:
- Antioxidants: Ingredients like Green Tea Extract, Grape Seed Extract, and Alpha Lipoic Acid help neutralize free radicals that cause tissue degradation.
- Minerals: Copper and Manganese are essential co-factors that help strengthen immature collagen and influence the size of collagen fibers in tendons and ligaments.
Summary Table: Joint Benefits
Ingredient
Primary Action on Joints
Arthred® Collagen
Stimulates chondrocytes to repair and rebuild cartilage.
Hyaluronic Acid
Increases synovial fluid for better joint lubrication and cushioning.
Vitamin C and Zinc
Essential for the synthesis of new collagen fibres.
Manganese & Copper
Strengthens the structural integrity of ligaments and tendons.
“As a Consultant Orthopaedic Surgeon, I am acutely aware of the importance of maintaining joint health, not only for mobility but for overall quality of life. In clinical practice, we often focus on structural interventions, but nutritional support plays an equally valuable role in supporting long term musculoskeletal function.”
Dr. Lorenzo Garagnani
Expert Council
Post-Surgical Healing after a Knee or Hip Replacement
If you are recovering from an injury, Totally Derma® acts as a powerful "internal repair kit" for injury recovery. It focuses on replenishing the structural proteins that make up your ligaments, tendons, and cartilage.
If your injury requires surgery, Totally Derma® is frequently recommended by clinicians to speed up wound healing. By mimicking the body's natural "injury signal," the high concentration of peptides triggers fibroblasts to work faster at the surgical site, potentially reducing scarring and speeding up the closure of the incision.
Totally Derma® for staying physically active
The Totally Derma® formulation is a powerhouse for anyone trying to stay physically active. Unlike standard collagen supplements that only focus on Type I (skin), it uses a specific pharmaceutical-grade bovine collagen (Arthred®) that targets the entire musculoskeletal system as well as the aesthetic.
“Our Pharmacy have a lot of customers who are keen runners, who previously were supplementing with chondroitin, glucosamine and MSM. The Totally Derma® formulation now solves all their joint issues.”
Gould Pharmacy
London, UK
How can Totally Derma® support a physically active lifestyle
1. Joint Lubrication & Flexibility
The standout feature for athletes is the high dose of Hyaluronic Acid (210mg). In the world of fitness, this acts like "grease for the wheels."
- The Benefit: It increases the viscosity of synovial fluid (the liquid between your joints), which reduces friction and "crunchiness" during high-impact activities like running or lifting.
- The Result: Improved range of motion and less stiffness the morning after a heavy session.
“I don’t have knee pain anymore. I work out quite regularly and every now and then I would have a bout of knee pain that forced me to slow down or stop my regime. Since taking Totally Derma®, I have been pain-free, and my joints have been more supple than ever. So, I wholeheartedly recommend taking Totally Derma if you want to improve your skin and joints.”
Eva
London, UK
2. Connective Tissue Repair
While many competitors provide 2,000mg to 5,000mg of collagen, Totally Derma® delivers 10,000mg of Arthred® hydrolysed collagen per serving in 2-3 kDa weight. This means 95% absorption.
- Tendon & Ligament Support: It contains Type II collagen, which is the primary component of cartilage. This helps reinforce the "cables" of your body, potentially reducing the risk of strains or tears during explosive movements.
- Bioavailability: It is pre-digested (hydrolysed) into tiny peptides, meaning your body can absorb up to 95% of it to start repairs quickly after exercise-induced micro-trauma.
Totally Derma® contains 10,000mg of Arthred® amino acid peptides, a pharmaceutical-grade hydrolysed bovine collagen. It is rich in specific amino acids glycine, proline and glutamine which are the primary building blocks used by the body to repair the delicate gut tissue that lines the gastrointestinal tract. L-Glutamine is also a specific amino acid which can repair and reverse the damaging effects of Leaky Gut Syndrome. Totally Derma® contains a very high amount of L-glutamine in its formulation.
“Two of the patients on the clinical study commented that the product really helped their joints - they commented that their knees did not hurt when running and now they have been finished for a week, their knees hurt.”
Prof E. Briden
Dermatologist US (Totally Derma® Clinical Skin Study/data on file)
Quick Comparison for the Active User
Feature
Collagen Dose
Joint Support
Collagen Type
Best Time
Standard "Beauty" Collagen
2,500mg - 5,000mg (Low)
Often 0mg or <50mg
Usually just Type I or III
Anytime
Totally Derma®
10,000mg (High)
210mg Hyaluronic Acid
Types I, II, & III
Before bed (peaks during sleep repair)
Feature
Collagen Dose
Joint Support
Collagen Type
Best Time
Standard "Beauty" Collagen
2,500 - 5,000 mg (Low)
Often 0mg or <50mg
Usually just Type I or III
Anytime
Feature
Collagen Dose
HA Content
Absorption
Key Focus
Totally Derma®
10,000mg (High)
210mg Hyaluronic Acid
Types I, II, & III
Before bed (peaks during sleep repair)
The Verdict
If you are active, you will notice the joint comfort first. Most users report feeling "less creaky" within 3 to 4 weeks. Because it also supports gut health (which is often compromised by the stress of heavy training), it is a solid all-in-one for systemic recovery.
Pro-Tip: For the best results in muscle and joint repair, try to take it in the evening. Most collagen synthesis happens during the first few hours of deep sleep!
Replenish
re•plen•ish
verb
1. fill (something) up again.
◦ restore a former level or condition
Rejuvenate
re•ju•ve•nate
verb
1. give new energy or vigour to; revitalise.
◦ restore a youthful appearance to
Repair
re•pair
verb
1. fix or mend (something suffering from damage).
Real Client Stories
Hear directly from people who transformed their skin health
I’ve been taking Totally Derma myself for a few years now. It's life changing. It stands apart from most other collagen based products with its quality of ingredients and how it’s formulated to stay within the body. I refer to it as the ‘Magic powder’ and that says it all ! Amazing product
Cutis Aesthetics
Happy Customer
My job involves standing for long hours at a time. I had constant pain in my joints, but after using Totally Derma it has really diminished my pain. I also find great improvements in my hair, skin and my nails. My hair is thicker and my nails are growing longer and stronger and my skin feels smoother and less wrinkled. I am 69 years old and I would not hesitate to recommend this product!
Pierre Vassiliou
Happy Customer
Totally Derma has been my bedtime drink for about four years and I love it. My 63-year old skin is more plump, my joints are strong and my gut seems healthy and happy! This collagen drink is fabulous and will forever be a step in my evening ritual.
Carla Bolsius
Happy Customer
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The Science Behind Wellness
Explore the clinical research and evidence supporting our wellness formulations